概述

  • 产品名称
  • 描述
    兔多克隆抗体to BCCIP
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide from the center region of human BCCIP, conjugated to KLH

  • 阳性对照
    • A375 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab71473 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Detects a band of approximately 33 kDa.

靶标

  • 功能
    May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).
  • 组织特异性
    Expressed at high levels in testis and skeletal muscle and at lower levels in brain, heart, kidney, liver, lung, ovary, pancreas, placenta, and spleen.
  • 序列相似性
    Belongs to the BCP1 family.
  • 发展阶段
    Isoform 1 is expressed throughout the cell cycle. Isoform 2 is expressed following mitosis and peaks in the G1/S phase of the cell cycle.
  • 细胞定位
    Nucleus. Colocalizes with BRCA2 in discrete nuclear foci.
  • Information by UniProt
  • 数据库链接
  • 别名
    • bccip antibody
    • BCCIP_HUMAN antibody
    • BCCIPalpha antibody
    • BCCIPbeta antibody
    • BRCA2 and CDKN1A interacting protein antibody
    • BRCA2 and CDKN1A-interacting protein antibody
    • BRCA2 and Cip1/p21 interacting protein antibody
    • Cdk inhibitor p21 binding protein antibody
    • P21 and CDK associated protein 1 antibody
    • P21- and CDK-associated protein 1 antibody
    • Protein TOK-1 antibody
    • Protein TOK1 antibody
    • TOK 1 antibody
    • TOK 1alpha antibody
    • TOK 1beta antibody
    • TOK1 antibody
    see all

图片

实验方案

文献

ab71473 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab71473.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册