概述

  • 产品名称Anti-BCCIP抗体
    参阅全部 BCCIP 一抗
  • 描述
    兔多克隆抗体to BCCIP
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Lizard, Gorilla
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 300-350 of Human BCCIP (NP_510868.1).

  • 阳性对照
    • Human Breast Carcinoma, Colon Carcinoma, Ovarian Carcinoma and Testicular Seminoma tissues

性能

应用

Our Abpromise guarantee covers the use of ab113288 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

靶标

  • 功能May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).
  • 组织特异性Expressed at high levels in testis and skeletal muscle and at lower levels in brain, heart, kidney, liver, lung, ovary, pancreas, placenta, and spleen.
  • 序列相似性Belongs to the BCP1 family.
  • 发展阶段Isoform 1 is expressed throughout the cell cycle. Isoform 2 is expressed following mitosis and peaks in the G1/S phase of the cell cycle.
  • 细胞定位Nucleus. Colocalizes with BRCA2 in discrete nuclear foci.
  • Information by UniProt
  • 数据库链接
  • 别名
    • bccip antibody
    • BCCIP_HUMAN antibody
    • BCCIPalpha antibody
    • BCCIPbeta antibody
    • BRCA2 and CDKN1A interacting protein antibody
    • BRCA2 and CDKN1A-interacting protein antibody
    • BRCA2 and Cip1/p21 interacting protein antibody
    • Cdk inhibitor p21 binding protein antibody
    • P21 and CDK associated protein 1 antibody
    • P21- and CDK-associated protein 1 antibody
    • Protein TOK-1 antibody
    • Protein TOK1 antibody
    • TOK 1 antibody
    • TOK 1alpha antibody
    • TOK 1beta antibody
    • TOK1 antibody
    see all

Anti-BCCIP antibody 图像

  • ab113288, at 1/250 dilution, staining BCCIP in formalin-fixed, paraffin-embedded Human Colon Carcinoma by Immunohistochemistry with DAB staining.
  • ab113288, at 1/250 dilution, staining BCCIP in formalin-fixed, paraffin-embedded Human testicular seminoma by Immunohistochemistry with DAB staining.
  • ab113288, at 1/100 dilution, staining BCCIP in formalin-fixed, paraffin-embedded Human breast carcinoma by Immunohistochemistry. Detection: Red-fluorescent Goat anti-Rabbit IgG-heavy and light chain cross-adsorbed Antibody DyLight® 594 Conjugated used at a dilution of 1/100.

Anti-BCCIP antibody (ab113288)参考文献

ab113288 has not yet been referenced specifically in any publications.

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