概述

  • 产品名称Anti-BBOX1抗体
    参阅全部 BBOX1 一抗
  • 描述
    小鼠单克隆抗体to BBOX1
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 278-388 of Human BBOX1

性能

应用

Our Abpromise guarantee covers the use of ab56350 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
    • 组织特异性Highly expressed in kidney; moderately expressed in liver; very low expression in brain.
    • 通路Amine and polyamine biosynthesis; carnitine biosynthesis.
    • 序列相似性Belongs to the gamma-BBH/TMLD family.
    • 细胞定位Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 2-oxoglutarate dioxygenase antibody
      • BBH antibody
      • BBOX 1 antibody
      • BBOX antibody
      • Bbox1 antibody
      • BODG_HUMAN antibody
      • Butyrobetaine (gamma) 2 oxoglutarate dioxygenase (gamma butyrobetaine hydroxylase) 1 antibody
      • G BBH antibody
      • Gamma BBH antibody
      • Gamma butyrobetaine 2 oxoglutarate dioxygenase 1 antibody
      • Gamma butyrobetaine dioxygenase antibody
      • Gamma butyrobetaine hydroxylase antibody
      • Gamma-BBH antibody
      • Gamma-butyrobetaine antibody
      • Gamma-butyrobetaine dioxygenase antibody
      • Gamma-butyrobetaine hydroxylase antibody
      see all

    Anti-BBOX1 antibody 图像

    • BBOX1 antibody (ab56350) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human kidney.
    • Western blot against tagged recombinant protein immunogen using ab56350 BBOX1 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa

    Anti-BBOX1 antibody (ab56350)参考文献

    This product has been referenced in:
    • Couturier A  et al. Pharmacological doses of niacin stimulate the expression of genes involved in carnitine uptake and biosynthesis and improve the carnitine status of obese Zucker rats. BMC Pharmacol Toxicol 15:37 (2014). WB ; Rat . Read more (PubMed: 25012467) »
    • Fischer M  et al. Activities of gamma-butyrobetaine dioxygenase and concentrations of carnitine in tissues of pigs. Comp Biochem Physiol A Mol Integr Physiol 153:324-31 (2009). Read more (PubMed: 19285565) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"