Anti-Bassoon抗体(ab110426)

概述

  • 产品名称
    Anti-Bassoon抗体
    参阅全部 Bassoon 一抗
  • 描述
    兔多克隆抗体to Bassoon
  • 特异性
    No cross-reactivity to Piccolo. Multiple isoforms can be detected.
  • 经测试应用
    适用于: IHC-Fr, IHC-P, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Fusion protein with His tag, corresponding to amino acids 786-1041 of Human Bassoon.

  • 阳性对照
    • Mouse and Rat brain lysates; Neuromuscular junction whole muscle tissue from adult mouse.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液
    pH: 7.40
    Preservative: 0.09% Sodium azide
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab110426 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.
WB 1/1000. Predicted molecular weight: 416 kDa. For large isoforms reduce dilution.

靶标

  • 功能
    Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses. Involved in the formation of the retinal photoreceptor ribbon synapses.
  • 组织特异性
    Exclusively expressed in brain.
  • 翻译后修饰
    Myristoylated. The N-terminal myristoylation is not sufficient for presynaptic localization.
  • 细胞定位
    Cytoplasm. Cell junction > synapse > synaptosome. Cytoplasm > cytoskeleton. Localized to the active zone of presynaptic density.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Bassoon protein antibody
    • bsn antibody
    • BSN_HUMAN antibody
    • KIAA0434 antibody
    • Neuronal double zinc finger protein antibody
    • Presynaptic cytomatrix protein antibody
    • Protein bassoon antibody
    • Zinc finger protein 231 antibody
    • ZNF 231 antibody
    • ZNF231 antibody
    see all

图片

  • All lanes : Anti-Bassoon antibody (ab110426) at 1/1000 dilution

    Lane 1 : Rat brain lysate
    Lane 2 : Mouse brain lysate

    Lysates/proteins at 10 µg per lane.


    Predicted band size : 416 kDa
  • Immunofluorescence of Neuromuscular junction whole muscle samples from adult mouse, stained with ab110426 at 1/400 dilution. Secondary (Alexa 488 goat antimouse IgG, IgM (H+L). Note: bright staining of the NMJ very selectively and in some terminals, very brightly.

文献

ab110426 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for contacting us.

We have 4 antibodies in our catalog raised against Bassoon: ab82958 (mouse), ab76065 (rabbit), ab110426 (rabbit) and ab101772 (goat).

Could you please let me know what kind of IHC you are planning to pe...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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