概述

  • 产品名称Anti-BAPX1抗体
    参阅全部 BAPX1 一抗
  • 描述
    兔多克隆抗体to BAPX1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rabbit, Chicken, Guinea pig, Cow, Dog
  • 免疫原

    A synthetic peptide corresponding to a region within the N terminal amino acids 2-51(

    AVRGANTLTSFSIQAILNKKEERGGLAAPEGRPAPGGTAASVAAAPAVCC

    ) of Human BAPX1, NP_001180.

  • 阳性对照
    • Jurkat cell lysate

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab85429 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus.
  • 组织特异性Expressed at highest levels in cartilage, bone (osteosarcoma) and gut (small intestine and colon), whereas moderate expression is seen in trachea and brain. Expressed in visceral mesoderm and embryonic skeleton.
  • 疾病相关Defects in NKX3-2 are the cause of spondylo-megaepiphyseal-metaphyseal dysplasia (SMMD) [MIM:613330]. It is a skeletal dysplasia characterized by disproportionate short stature with a short and stiff neck and trunk, relatively long limbs that may show flexion contractures of the distal joints, delayed and impaired ossification of the vertebral bodies, the presence of large epiphysea ossification centers and wide growth plates in the long tubular bones and numerous pseudoepiphyses of the short tubular bones in hands and feet.
  • 序列相似性Belongs to the NK-3 homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Bagpipe homeobox 1 antibody
    • Bagpipe homeobox homolog 1 antibody
    • Bagpipe homeobox protein homolog 1 antibody
    • Bagpipe homeobox, Drosophila, homolog of, 1 antibody
    • BAPX 1 antibody
    • Homeobox protein NK-3 homolog B antibody
    • Homeobox protein Nkx 3.2 antibody
    • Homeobox protein Nkx-3.2 antibody
    • MGC138171 antibody
    • NK3 homeobox 2 antibody
    • NKX3 2 antibody
    • NKX3-2 antibody
    • NKX3.2 antibody
    • NKX3.2, mouse, homolog of antibody
    • NKX32_HUMAN antibody
    • NKX3B antibody
    • OTTHUMP00000115816 antibody
    • SMMD antibody
    see all

Anti-BAPX1 antibody 图像

  • Anti-BAPX1 antibody (ab85429) at 1 µg/ml (in 5% skim milk / PBS buffer) + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 35 kDa
    Observed band size : 35 kDa
    Additional bands at : 60 kDa,65 kDa. We are unsure as to the identity of these extra bands.

Anti-BAPX1 antibody (ab85429)参考文献

ab85429 has not yet been referenced specifically in any publications.

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