概述

  • 产品名称
  • 描述
    兔多克隆抗体to BANP
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rabbit, Horse, Guinea pig, Cow, Dog, Chimpanzee, Rhesus monkey, Chinese hamster, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 425-469 (GQLLEATRIP CLLAPSVFKA SSGQVLQGAQ LIAVASSDPA AAGVDG) of human BANP (SwissProt Q96GJ7).

  • 阳性对照
    • Human breast tumor; mouse squamous cell carcinoma.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    The antibody was affinity purified using an epitope specific to BANP immobilized on solid support.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab84376 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明
    IHC-P: 1/100 - 1/500.
    Epitope exposure is recommended.
    Epitope exposure with citrate buffer will enhance staining.

    Likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest.
    • 组织特异性
      Down-regulated in breast cancer cell lines.
    • 序列相似性
      Belongs to the BANP/SMAR1 family.
      Contains 1 BEN domain.
    • 细胞定位
      Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AAH09424 antibody
      • Banp antibody
      • BANP_HUMAN antibody
      • BEN domain-containing protein 1 antibody
      • BEND1 antibody
      • BTG3 associated nuclear protein isoform a antibody
      • Btg3-associated nuclear protein antibody
      • DKFZp761H172 antibody
      • FLJ 10177 antibody
      • FLJ 20538 antibody
      • FLJ10177 antibody
      • FLJ20538 antibody
      • Protein BANP antibody
      • Scaffold/Matrix associated region 1 antibody
      • Scaffold/matrix-associated region-1-binding protein antibody
      • SMAR 1 antibody
      • SMAR1 antibody
      • SMARBP 1 antibody
      • SMARBP1 antibody
      see all

    图片

    • ab84376, at a 1/250 dilution, staining BANP in formalin fixed, paraffin embedded human breast tumor by Immunohistochemistry.
      Detection: by DAB staining
    • ab84376, at a 1/250 dilution, staining BANP in formalin fixed, paraffin embedded mouse squamous cell carcinoma by Immunohistochemistry.
      Detection: by DAB staining

    文献

    ab84376 has not yet been referenced specifically in any publications.

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