概述

  • 产品名称Anti-BANP抗体
    参阅全部 BANP 一抗
  • 描述
    兔多克隆抗体to BANP
  • 经测试应用适用于: IP, IHC-P, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Rabbit, Horse, Guinea pig, Cow, Dog, Chimpanzee, Rhesus monkey, Chinese Hamster, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residue 425 and the C-terminus (residue 469) of human BANP (TrEMBL entry Q96GJ7)

  • 阳性对照
    • Nuclear extract from HeLa cells

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 8mM PBS, 60mM Citrate, 150mM Tris, pH 7 to 8
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab72076 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP 1/200 - 1/2500.
IHC-P 1/2000 - 1/10000.
WB 1/10000 - 1/25000. Predicted molecular weight: 59 kDa.

靶标

  • 功能Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest.
  • 组织特异性Down-regulated in breast cancer cell lines.
  • 序列相似性Belongs to the BANP/SMAR1 family.
    Contains 1 BEN domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AAH09424 antibody
    • Banp antibody
    • BANP_HUMAN antibody
    • BEN domain-containing protein 1 antibody
    • BEND1 antibody
    • BTG3 associated nuclear protein isoform a antibody
    • Btg3-associated nuclear protein antibody
    • DKFZp761H172 antibody
    • FLJ 10177 antibody
    • FLJ 20538 antibody
    • FLJ10177 antibody
    • FLJ20538 antibody
    • Protein BANP antibody
    • Scaffold/Matrix associated region 1 antibody
    • Scaffold/matrix-associated region-1-binding protein antibody
    • SMAR 1 antibody
    • SMAR1 antibody
    • SMARBP 1 antibody
    • SMARBP1 antibody
    see all

Anti-BANP antibody 图像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung carcinoma (left) and mouse renal cell carcinoma (right) tissues labelling BANP with ab72076 at 1/5000 (0.2µg/ml). Setection: DAB.
  • All lanes : Anti-BANP antibody (ab72076) at 0.1 µg/ml

    Lane 1 : Nuclear extract from HeLa cells at 5 µg
    Lane 2 : Nuclear extract from HeLa cells at 20 µg


    Predicted band size : 59 kDa
    Observed band size : 70 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 150 kDa,250 kDa. We are unsure as to the identity of these extra bands.

Anti-BANP antibody (ab72076)参考文献

ab72076 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab72076.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"