概述

  • 产品名称
  • 描述
    兔多克隆抗体to BANP
  • 经测试应用
    适用于: IHC-P, ICC/IF, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to a 14 amino acid internal sequence of Human BANP (NP_001167014).

  • 阳性对照
    • Mouse kidney tissue lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab105404 is purified by affinity chromatography via a peptide column.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab105404 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 56 kDa.

靶标

  • 功能
    Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest.
  • 组织特异性
    Down-regulated in breast cancer cell lines.
  • 序列相似性
    Belongs to the BANP/SMAR1 family.
    Contains 1 BEN domain.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AAH09424 antibody
    • Banp antibody
    • BANP_HUMAN antibody
    • BEN domain-containing protein 1 antibody
    • BEND1 antibody
    • BTG3 associated nuclear protein isoform a antibody
    • Btg3-associated nuclear protein antibody
    • DKFZp761H172 antibody
    • FLJ 10177 antibody
    • FLJ 20538 antibody
    • FLJ10177 antibody
    • FLJ20538 antibody
    • Protein BANP antibody
    • Scaffold/Matrix associated region 1 antibody
    • Scaffold/matrix-associated region-1-binding protein antibody
    • SMAR 1 antibody
    • SMAR1 antibody
    • SMARBP 1 antibody
    • SMARBP1 antibody
    see all

图片

  • Immunofluorescence of BANP in Human kidney tissue with ab105404 at 20 ug/mL.

  • Immunohistochemistry of Human kidney tissue with ab105404 at 10 μg/mL.

  • Lane 1 : Anti-BANP antibody (ab105404) at 1 µg/ml
    Lane 2 : Anti-BANP antibody (ab105404) at 2 µg/ml

    Lane 1 : Mouse kidney tissue lysate
    Lane 2 : Mouse kidney tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 56 kDa

文献

ab105404 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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