Anti-Bak抗体, prediluted (ab15179)

概述

  • 产品名称Anti-Bak抗体, prediluted
    参阅全部 Bak 一抗
  • 描述
    兔多克隆抗体to Bak, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Hamster
  • 免疫原

    Synthetic peptide (Human) (N terminal).

  • 阳性对照
    • Tested with A431 cells and tonsil.

性能

  • 形式Prediluted
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: 1% BSA, 50mM Tris, pH 7.6
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab15179 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Ready diluted. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
    • 组织特异性Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
    • 序列相似性Belongs to the Bcl-2 family.
    • 结构域Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
    • 细胞定位Mitochondrion membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Apoptosis regulator BAK antibody
      • BAK antibody
      • BAK like antibody
      • Bak NT antibody
      • BAK_HUMAN antibody
      • Bak1 antibody
      • Bcl 2 homologous antagonist/killer antibody
      • Bcl 2 like 7 protein antibody
      • Bcl-2 homologous antagonist/killer antibody
      • Bcl-2-like protein 7 antibody
      • BCL2 antagonist/killer 1 antibody
      • Bcl2 like 7 Protein antibody
      • Bcl2-L-7 antibody
      • BCL2L7 antibody
      • CDN1 antibody
      • Cell death inhibitor 1 antibody
      • MGC117255 antibody
      • MGC3887 antibody
      • NBak antibody
      • Pro apoptotic protein BAK antibody
      see all

    Anti-Bak antibody, prediluted 图像

    • Human tonsil stained with ab15179.

    Anti-Bak antibody, prediluted (ab15179)参考文献

    ab15179 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. The concentration of ab32371 is 0.025 mg/mL and the concentration of ab15179 for the current lot is 1 ug/mL. I hope this information helps, please do not hesitate to contact us if you need any more advice or information.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"