概述

  • 产品名称
  • 描述
    兔多克隆抗体to Bak
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide, corresponding to amino acids 23-38 (with C-terminal Lysine added) of Human Bak.

  • 阳性对照
    • A431 whole cell lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 15mM Sodium Azide
    Constituents: 0.01M PBS, pH 7.4
  • Concentration information loading...
  • 纯度
    IgG fraction
  • 纯化说明
    Whole antiserum is fractionated and then further purified by ion-exchange chromatography to provide the IgG fraction of antiserum that is essentially free of other rabbit serum proteins.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab10430 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
  • 应用说明
    IHC-P: 1/100 (human colon adenocarcinoma).
    WB: 1/2000. Detects a band of approximately 28 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
    • 组织特异性
      Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
    • 序列相似性
      Belongs to the Bcl-2 family.
    • 结构域
      Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
    • 细胞定位
      Mitochondrion membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Apoptosis regulator BAK antibody
      • BAK antibody
      • BAK like antibody
      • Bak NT antibody
      • BAK_HUMAN antibody
      • Bak1 antibody
      • Bcl 2 homologous antagonist/killer antibody
      • Bcl 2 like 7 protein antibody
      • Bcl-2 homologous antagonist/killer antibody
      • Bcl-2-like protein 7 antibody
      • BCL2 antagonist/killer 1 antibody
      • Bcl2 like 7 Protein antibody
      • Bcl2-L-7 antibody
      • BCL2L7 antibody
      • CDN1 antibody
      • Cell death inhibitor 1 antibody
      • MGC117255 antibody
      • MGC3887 antibody
      • NBak antibody
      • Pro apoptotic protein BAK antibody
      see all

    Anti-Bak antibody (ab10430)参考文献

    ab10430 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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