概述

  • 产品名称Anti-Bag5抗体
    参阅全部 Bag5 一抗
  • 描述
    小鼠单克隆抗体to Bag5
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-448 of Human Bag5

性能

应用

Our Abpromise guarantee covers the use of ab56738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 51 kDa.
ICC/IF Use at an assay dependent concentration. PubMed: 24475098

靶标

  • 功能Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.
  • 序列相似性Contains 5 BAG domains.
  • 结构域The fifth BAG domain is responsible for the interaction with HSP70 nucleotide-binding domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BAG family molecular chaperone regulator 5 antibody
    • BAG-5 antibody
    • BAG5 antibody
    • BAG5_HUMAN antibody
    • Bcl 2 associated athanogene 5 antibody
    • Bcl-2-associated athanogene 5 antibody
    • BCL2 associated athanogene 5 antibody
    • KIAA0873 antibody
    see all

Anti-Bag5 antibody 图像



  • Predicted band size : 51 kDa
    Bag5 antibody (ab56738) at 1ug/lane + Jurkat cell lysate at 25ug/lane.

Anti-Bag5 antibody (ab56738)参考文献

This product has been referenced in:
  • Wang X  et al. BAG5 protects against mitochondrial oxidative damage through regulating PINK1 degradation. PLoS One 9:e86276 (2014). ICC/IF ; Human . Read more (PubMed: 24475098) »
  • Boiani M  et al. The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737. J Biol Chem 288:6980-90 (2013). WB ; Human . Read more (PubMed: 23341456) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"