概述

  • 产品名称Anti-BAG2抗体[EPR3567]
    参阅全部 BAG2 一抗
  • 描述
    兔单克隆抗体[EPR3567] to BAG2
  • 经测试应用适用于: WB, IP, IHC-P, ICC, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human BAG2 aa 1-100 (N terminal).

  • 阳性对照
    • Jurkat, HeLa and HepG2 cell lysates; human ovarian carcinoma tissue.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Produced using Abcam's RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5, 675, 063 and/or 7, 429, 487.

性能

应用

Our Abpromise guarantee covers the use of ab79406 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/5000. Detects a band of approximately 24 kDa (predicted molecular weight: 24 kDa).
IP 1/10.
IHC-P 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC 1/100 - 1/250.
Flow Cyt 1/60.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.
  • 序列相似性Contains 1 BAG domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BAG 2 antibody
    • BAG family molecular chaperone regulator 2 antibody
    • BAG-2 antibody
    • BAG-family molecular chaperone regulator-2 antibody
    • Bag2 antibody
    • BAG2_HUMAN antibody
    • BCL 2 associated athanogene 2 antibody
    • Bcl-2-associated athanogene 2 antibody
    • BCL2 associated athanogene 2 antibody
    • BCL2-associated athanogene 2 antibody
    • dJ417I1.2 (BAG family molecular chaperone regulator 2) antibody
    • dJ417I1.2 antibody
    • KIAA0576 antibody
    • MGC149462 antibody
    • OTTHUMP00000016668 antibody
    see all

Anti-BAG2 antibody [EPR3567] 图像

  • All lanes : Anti-BAG2 antibody [EPR3567] (ab79406) at 1/5000 dilution

    Lane 1 : Jurkat cell lysate
    Lane 2 : HeLa cell lysate
    Lane 3 : HepG2 cell lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat anti-rabbit HRP at 1/2000 dilution

    Predicted band size : 24 kDa
    Observed band size : 24 kDa
  • ab79406, at 1/100 dilution, staining BAG2 in human ovarian carcinoma by Immunohistochemistry using paraffin-embedded tissue.

Anti-BAG2 antibody [EPR3567] (ab79406)参考文献

This product has been referenced in:
  • Azoitei N  et al. Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33. J Exp Med 209:697-711 (2012). WB . Read more (PubMed: 22451720) »

See 1 Publication for this product

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