Anti-Bacillus anthracis lethal factor抗体[BAL0105] (HRP) (ab24451)


  • 产品名称Anti-Bacillus anthracis lethal factor抗体[BAL0105] (HRP)
    参阅全部 Bacillus anthracis lethal factor 一抗
  • 描述
    小鼠单克隆抗体[BAL0105] to Bacillus anthracis lethal factor (HRP)
  • 偶联物HRP
  • 特异性Lethal factor antigen of Bacillus anthracis.
  • 经测试应用适用于: Sandwich ELISA, ELISAmore details
  • 种属反应性
    Reacts with Bacillus anthracis. Not yet tested in other species.
  • 免疫原

    Highly purified lethal factor antigen of Bacillus anthracis.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液pH: 7.40
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号BAL0105
  • 骨髓瘤Sp2/0
  • 同种型IgG1
  • 研究领域


Our Abpromise guarantee covers the use of ab24451 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Sandwich ELISA Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution. Can be paired for ELISA with Mouse monoclonal [BAL0106] to Bacillus anthracis lethal factor (ab8243). Can be used as capture antibody


  • 相关性The protease enzyme Lethal Factor (LF) is one of the three proteins (LF, EF & PA) composing the anthrax toxin produced by Bacillus anthracis, a bacteria which can infect many mammalian species and that may be fatal. LF is not toxic by itself, but when associated with Protective Antigen (PA), can then gain entry to cells. Once inside the cell, LF then cleaves the N terminal of most dual specificity mitogen activated protein kinase kinases (MAPKKs or MAP2Ks) (except for MAP2K5). Cleavage invariably occurs within the N terminal proline rich region preceding the kinase domain, thus disrupting a sequence involved in directing specific protein protein interactions necessary for the assembly of signaling complexes. There may be other cytosolic targets of LF involved in cytotoxicity. The proteasome may mediate a toxic process initiated by LF in the cell cytosol involving degradation of unidentified molecules that are essential for macrophage homeostasis. This is an early step in LF intoxication, but it is downstream of the cleavage by LF of MEK1 or other putative substrates.
  • 细胞定位secreted
  • 别名
    • Anthrax lethal toxin endopeptidase component antibody
    • Anthrax LF antibody
    • Lef antibody
    • Lethal factor antibody
    • LF antibody
    see all

Anti-Bacillus anthracis lethal factor antibody [BAL0105] (HRP) (ab24451)参考文献

ab24451 has not yet been referenced specifically in any publications.

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I have had the oportunity to look over the data regarding the antibodies we had talked about this morning. I am confident that your assessment of those products we correct as ab8242 and ab24451 have been created ...

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Thank you for calling Abcam yesterday. I think there is an error in the datasheet for ab24451, I do not think there is sodium azide in the storage buffer. I am continuing to consult with my colleagues about this and I will contact you again, as soon as...

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Thank you for your enquiry. Both ab8243 and ab24451 were generated using highly purified lethal factor antigen of Bacillus anthracis. These two antibodies can be used together in a sandwich ELISA where ab8243 is the coating antibody and ab24451 is the ...

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