概述

  • 产品名称Anti-Baboon抗体
    参阅全部 Baboon 一抗
  • 描述
    兔多克隆抗体to Baboon
  • 特异性The antibody is unique to Baboon protein.
  • 经测试应用适用于: IP, WB, ICCmore details
  • 种属反应性
    与反应: Drosophila melanogaster
  • 免疫原

    Synthetic peptide:

    CNKNENMKRIFETDYVPHRLTS

    , corresponding to N terminal amino acids 200-221 of Drosophilia melanogaster Baboon. The peptide was amidated for conjugation.

  • 阳性对照
    • D. melanogaster extracts.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: BSA, Glycerol, Sodium chloride, HEPES, Potassium chloride, chaotropic agents, pH 7.4
    The buffer contains primary amines and is not suitable for conjugation via NH2 group.
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified against immobilized antigen based affinity chromatography which yielded an epitope specific antibody.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab14681 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP
WB
ICC
  • 应用说明ICC: Use at an assay dependent dilution.
    IP: >1/200.
    WB: >1/500. Detects a band of approximately 73 kDa

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Transmembrane receptor Patched regulates several developmental processes in both invertebrates and vertebrates. In higher vertebrates the patched (Ptc) also acts as a tumor suppressor. The patched receptor signaling involves negatively regulating a GPCR, smoothened. The binding Hedgehog ligand to Ptc removes the negative interaction of Ptc, and allows the signaling by smoothened. It has been shown that during head morphogenesis in D. melanogaster, Ptc positively interacts with smoothened, which leads to stimulation of Activin type 1 receptor Baboon, and activation of cell proliferation in the eye antennal disc. The expression of activated Baboon in the Ptc domain in Ptc mutant background completely abolish the head developmental defects.
    • 数据库链接
      • 别名
        • ATR1 antibody
        • AtrI antibody
        • Bab antibody
        • Babo antibody
        • G protein coupled receptor kinase 3 antibody
        • STKE antibody
        see all

      Anti-Baboon antibody 图像

      • ab14681 used at a 1/50 dilution staining Baboon in Drosophila brain tissue sections by Immunohistochemistry.
        Babo staining (magenta) overlapped with CD8::GFP expression (green). Scale bar: 20 µm.

      Anti-Baboon antibody (ab14681)参考文献

      This product has been referenced in:
      • Ng J TGF{beta} signals regulate axonal development through distinct Smad-independent mechanisms. Development 135:4025-35 (2008). IHC ; Drosophila melanogaster . Read more (PubMed: 19004854) »

      See 1 Publication for this product

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