Anti-BAALC抗体(ab77101)

概述

• 产品名称Anti-BAALC抗体
  参阅全部 BAALC 一抗
• 描述
  山羊多克隆抗体to BAALC
• 特异性ab77101 is expected to recognise BAALC isoform 1 (NP_079088.1) only.
• 经测试应用适用于: WB, ELISAmore details
• 种属反应性
  与反应: Mouse
  预测可用于: Rat, Human, Pig
• 免疫原

  Synthetic peptide: C-KQNGLQTTEA KRDAK, corresponding to internal sequence amino acids 101-115 of Human BAALC (NP_079088.1)

  Run BLAST with Run BLAST with
• 阳性对照
  • Human and mouse brain lysates.

性能

• 形式Liquid
• 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• 存储溶液Preservative: 0.02% Sodium Azide
  Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
• Concentration information loading...
• 纯度Immunogen affinity purified
• 纯化说明ab77101 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• 克隆多克隆
• 同种型IgG
• 研究领域
  • Cardiovascular
  • Blood
  • Other

  • Neuroscience
  • Neurology process
  • Neural Signal Transduction

相关产品

• Compatible Secondaries
  • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
  • Donkey Anti-Goat IgG H&L (HRP) (ab205723)
• Positive Controls
  • Recombinant Human BAALC protein (ab117684)
  • Recombinant Human BAALC protein (ab95394)

应用

靶标

• 功能May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A.
• 组织特异性Expressed by neural and hematopoietic cells. Expression is found both in normal early progenitor cells and in the most immature type of blasts in acute leukemia but not in mature hematopoietic cells. Isoform 2 and isoform 6 are expressed in the brain. Isoform 2 shows a low expression in neuroectoderm-derived tissues such as adrenal gland and no expression in bone marrow, peripheral blood lymphocytes or lymph nodes, or in tumors or cancer cell lines of nonneural tissue origin.
• 翻译后修饰Palmitoylation and myristoylation target the protein to the lipid rafts.
• 细胞定位Cytoplasm. Membrane. Postsynaptic lipid rafts.

• Target information above from: UniProt accession Q8WXS3 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 79870 Human
  • Entrez Gene: 118452 Mouse
  • Entrez Gene: 100170128 Pig
  • Entrez Gene: 140720 Rat
  • Omim: 606602 Human
  • SwissProt: Q8WXS3 Human
  • SwissProt: Q8VHV1 Mouse
  • SwissProt: Q8WNE9 Pig

  • SwissProt: Q920K5 Rat
  • Unigene: 533446 Human
  • Unigene: 233837 Mouse
  • Unigene: 19969 Rat

  see all
• 别名
  • BAALC antibody
  • BAALC_HUMAN antibody
  • Brain and acute leukemia cytoplasmic antibody

  • Brain and acute leukemia cytoplasmic protein antibody
  • FLJ12015 antibody

  see all