Anti-B3GNT3抗体(ab70156)
Key features and details
- Mouse polyclonal to B3GNT3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-B3GNT3抗体
参阅全部 B3GNT3 一抗 -
描述
小鼠多克隆抗体to B3GNT3 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein within Human B3GNT3. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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阳性对照
- B3GNT3 transfected 293T cell lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab70156于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
说明 |
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Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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相关性
B3GNT3 belongs to the glycosyltransferase 31 family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. B3GNT3 plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking. It is expressed in colon, jejunum, stomach, esophagus, placenta and trachea. -
细胞定位
Golgi apparatus membrane; Single pass type II membrane protein. -
数据库链接
- Entrez Gene: 10331 Human
- Omim: 605863 Human
- SwissProt: Q9Y2A9 Human
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别名
- B3GAL T8 antibody
- B3GALT8 antibody
- B3GN T3 antibody
see all
图片
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All lanes : Anti-B3GNT3 antibody (ab70156) at 1/500 dilution
Lane 1 : B3GNT3 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 43 kDa
Observed band size: 40 kDa why is the actual band size different from the predicted?
Additional bands at: 49 kDa, 51 kDa. We are unsure as to the identity of these extra bands.
数据表及文件
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Datasheet download
文献 (1)
ab70156 被引用在 1 文献中.
- Wang JS et al. B3GNT3 acts as a carcinogenic factor in endometrial cancer via facilitating cell growth, invasion and migration through regulating RhoA/RAC1 pathway-associated markers. Genes Genomics 43:447-457 (2021). PubMed: 33683574