兔多克隆抗体to B MyB (phospho S577 + S581)
Detects endogenous levels of B MyB only when phosphorylated at serine 577/581.
Synthetic phosphopeptide derived from human B MyB around the phosphorylation site of serine 577/581 (R-R-S
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg 2+ and Ca 2+), 150mM Sodium chloride, pH 7.4
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Immunogen affinity purified
Affinity purified from rabbit antiserum by affinity-chromatography using
epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration. PubMed: 23449447
1/500 - 1/1000. Detects a band of approximately 79 kDa (predicted molecular weight: 79 kDa).
Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene.
Contains 3 HTH myb-type DNA-binding domains.
Phosphorylated by cyclin A/CDK2 during S-phase. Phosphorylation at Thr-520 is probably involved in transcriptional activity.
Information by UniProt
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