Anti-B MyB (phospho S577 + S581)抗体(ab61000)
Key features and details
- Rabbit polyclonal to B MyB (phospho S577 + S581)
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-B MyB (phospho S577 + S581)抗体
参阅全部 B MyB 一抗 -
描述
兔多克隆抗体to B MyB (phospho S577 + S581) -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Rat -
免疫原
Synthetic peptide corresponding to Human B MyB (phospho S577 + S581).
Database link: P10244 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Without Mg2+ and Ca2+ -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
Affinity purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab61000于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/1000. Detects a band of approximately 79 kDa (predicted molecular weight: 79 kDa).
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说明 |
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WB
1/500 - 1/1000. Detects a band of approximately 79 kDa (predicted molecular weight: 79 kDa). |
靶标
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功能
Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene. -
序列相似性
Contains 3 HTH myb-type DNA-binding domains. -
翻译后修饰
Phosphorylated by cyclin A/CDK2 during S-phase. Phosphorylation at Thr-520 is probably involved in transcriptional activity. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 4605 Human
- Entrez Gene: 296344 Rat
- Omim: 601415 Human
- SwissProt: P10244 Human
- Unigene: 179718 Human
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别名
- B-Myb antibody
- BMyB antibody
- MGC15600 antibody
see all
图片
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab61000 被引用在 2 文献中.
- Werwein E et al. Intramolecular interaction of B-MYB is regulated through Ser-577 phosphorylation. FEBS Lett 594:4266-4279 (2020). PubMed: 32979888
- Werwein E et al. B-Myb switches from Cyclin/Cdk-dependent to Jnk- and p38 kinase-dependent phosphorylation and associates with SC35 bodies after UV stress. Cell Death Dis 4:e511 (2013). ICC/IF ; Mouse, Human . PubMed: 23449447