概述

  • 产品名称Anti-ATXN7L3抗体
    参阅全部 ATXN7L3 一抗
  • 描述
    兔多克隆抗体to ATXN7L3
  • 经测试应用适用于: WBmore details
    不适用于: IP
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Rhesus monkey, Gorilla
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 297-347 of Human ATXN7L3 (NP_001092303.1).

  • 阳性对照
    • HeLa and 293T whole cell lysates

性能

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应用

Our Abpromise guarantee covers the use of ab99947 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000 - 1/10000. Predicted molecular weight: 39 kDa.
  • 应用说明Is unsuitable for IP.
  • 靶标

    • 功能Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
    • 序列相似性Belongs to the SGF11 family.
      Contains 1 SCA7 domain.
      Contains 1 SGF11-type zinc finger.
    • 结构域The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.
      The C-terminal SGF11-type zinc-finger domain together with the C-terminal catalytic domain of USP22 forms the 'catalytic lobe' of the SAGA deubiquitination module.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AT7L3_HUMAN antibody
      • Ataxin 7 like 3 antibody
      • Ataxin 7 like protein 3 antibody
      • Ataxin-7-like protein 3 antibody
      • atxn7l3 antibody
      • SAGA associated factor 11 homolog antibody
      • SAGA-associated factor 11 homolog antibody
      see all

    Anti-ATXN7L3 antibody 图像

    • All lanes : Anti-ATXN7L3 antibody (ab99947) at 0.4 µg/ml

      Lane 1 : HeLa whole cell lysate at 50 µg
      Lane 2 : HeLa whole cell lysate at 15 µg
      Lane 3 : HeLa whole cell lysate at 5 µg
      Lane 4 : 293T whole cell lysate at 50 µg

      Developed using the ECL technique

      Predicted band size : 39 kDa


      Exposure time : 3 minutes

    Anti-ATXN7L3 antibody (ab99947)参考文献

    ab99947 has not yet been referenced specifically in any publications.

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