Anti-Attractin抗体(ab14567)

概述

  • 产品名称Anti-Attractin抗体
    参阅全部 Attractin 一抗
  • 描述
    兔多克隆抗体to Attractin
  • 经测试应用适用于: ICC/IF, ELISA, WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Human
  • 免疫原

    A 21 AA Peptide sequence near the C-terminus of mouse Attractin coupled to KLH. The sequence is 100% conserved in the 452 AA human KIAA0548 protein.

性能

应用

Our Abpromise guarantee covers the use of ab14567 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF 1/200.
ELISA 1/10000 - 1/50000.
WB 1/1000 - 1/5000. Predicted molecular weight: 160 kDa.

靶标

  • 功能Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system.
  • 组织特异性Isoform 2 is detected in plasma (at protein level). Expressed and secreted by activated T lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes.
  • 序列相似性Contains 1 C-type lectin domain.
    Contains 1 CUB domain.
    Contains 1 EGF-like domain.
    Contains 6 Kelch repeats.
    Contains 2 laminin EGF-like domains.
    Contains 4 PSI domains.
  • 翻译后修饰Heavily glycosylated.
  • 细胞定位Secreted and Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ATRN antibody
    • ATRN_HUMAN antibody
    • attractin 2 antibody
    • Attractin antibody
    • DPPT L antibody
    • DPPT-L antibody
    • KIAA0548 antibody
    • Mahogany homolog antibody
    • mahogany protein antibody
    • Mahogany, mouse, homolog of antibody
    • MGCA antibody
    see all

Anti-Attractin antibody (ab14567)参考文献

ab14567 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Loading amount 30 µg
Gel Running Conditions Reduced Denaturing (6%)
Sample Zebra finch Tissue lysate - whole (brain, skin, liver, muscle, and spleen)
Specification brain, skin, liver, muscle, and spleen
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 3% · Temperature: 25°C
Username

Abcam user community

Verified customer

提交于 Apr 10 2015

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Mouse Cell (melan-a (mouse melanocyte cell line))
Specification melan-a (mouse melanocyte cell line)
Fixative Paraformaldehyde
Permeabilization Yes - 0.025% Triton for 3 minutes
Blocking step Serum as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
Username

Dr. Teresa Gunn

Verified customer

提交于 Jul 23 2007

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"