概述

  • 产品名称Anti-ATRIP抗体
    参阅全部 ATRIP 一抗
  • 描述
    兔多克隆抗体to ATRIP
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee
  • 免疫原

    Synthetic peptide corresponding to a region between residue 100 to 150 of Human ATRIP (NP_569055.1)

  • 阳性对照
    • Human breast carcinoma and prostate carcinoma tissue

性能

应用

Our Abpromise guarantee covers the use of ab90614 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500. Perform enzymatic antigen retrieval before commencing with IHC staining protocol. Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.
    Likely to work with frozen sections.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
    • 组织特异性Ubiquitous.
    • 序列相似性Belongs to the ATRIP family.
    • 结构域The EEXXXDDL motif is required for the interaction with catalytic subunit PRKDC and its recruitment to sites of DNA damage.
    • 翻译后修饰Phosphorylated by ATR.
    • 细胞定位Nucleus. Redistributes to discrete nuclear foci upon DNA damage.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AGS1 antibody
      • ATIP antibody
      • ATM and Rad3 related interacting protein antibody
      • ATM and Rad3-related-interacting protein antibody
      • ATR interacting protein antibody
      • ATR-interacting protein antibody
      • Atrip antibody
      • ATRIP_HUMAN antibody
      • DKFZp762J2115 antibody
      • FLJ12343 antibody
      • MGC20625 antibody
      • MGC21482 antibody
      • MGC26740 antibody
      see all

    Anti-ATRIP antibody 图像

    • Immunohistochemical analysis of Human ATRIP in formalin-fixed paraffin-embedded human prostate carcinoma tissue using ab90614 at a dilution of 1/250

    Anti-ATRIP antibody (ab90614)参考文献

    ab90614 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"