参阅全部 ATRIP 一抗
Recombinant fragment: MGPGARRQGR IVQGRPEMCF CPPPTPLPPL RILTLGTHTP TPCSSPGSAA GTYPTMGSQA LPPGPMQTLI FFDMEATGLP FSQPKVTELC LLAVHRCALE , corresponding to amino acids 1-101 of Human ATRIP
- 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- 存储溶液Preservative: None
PBS, pH 7.2
Concentration information loading...
- 纯度Protein G purified
应用说明WB: Use at a concentration of 1-5 µg/ml.
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- 功能Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
- 序列相似性Belongs to the ATRIP family.
- 结构域The EEXXXDDL motif is required for the interaction with catalytic subunit PRKDC and its recruitment to sites of DNA damage.
- 翻译后修饰Phosphorylated by ATR.
- 细胞定位Nucleus. Redistributes to discrete nuclear foci upon DNA damage.
Information by UniProt
- AGS1 antibody
- ATIP antibody
- ATM and Rad3 related interacting protein antibody
Anti-ATRIP antibody (ab56956)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"