• 产品名称Anti-ATP6V1B1抗体
    参阅全部 ATP6V1B1 一抗
  • 描述
    兔多克隆抗体to ATP6V1B1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig, Saccharomyces cerevisiae
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 395-444 (LMKSAIGEGM TRKDHGDVSN QLYACYAIGK DVQAMKAVVG EEALTSEDLL) of Human ATP6V1B1 (NP_001683).

  • 阳性对照
    • HeLa cell lysate



Our Abpromise guarantee covers the use of ab98991 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 57 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • 功能Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
  • 组织特异性Expressed in the cochlea and endolymphatic sac.
  • 疾病相关Defects in ATP6V1B1 are the cause of distal renal tubular acidosis with deafness (dRTA-D) [MIM:267300]. Inheritance is autosomal recessive. Patients with recessive dRTA are severely affected, presenting with either acute illness or growth failure at a young age, and bilateral sensorineural deafness. Other features include low serum K(+) due to renal potassium wasting, and elevated urinary calcium. If untreated, this acidosis may result in dissolution of bone, leading to osteomalacia and rickets. Renal deposition of calcium salts (nephrocalcinosis) and renal stone formation commonly occur.
  • 序列相似性Belongs to the ATPase alpha/beta chains family.
  • 结构域The PDZ-binding motif mediates interactions with SLC9A3R1 and SCL4A7.
  • 细胞定位Endomembrane system. Endomembrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Atp6b1 antibody
    • ATP6V1B1 antibody
    • ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta 56/58 kDa, isoform 1 antibody
    • ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B, isoform 1 antibody
    • ATPase, H+ transporting, V1 subunit B, isoform 1 antibody
    • Endomembrane proton pump 58 kDa subunit antibody
    • H(+) transporting two sector ATPase 58kD subunit antibody
    • H+ ATPase beta 1 subunit antibody
    • kidney isoform antibody
    • Lysosomal 56/58kDa antibody
    • MGC32642 antibody
    • RTA1B antibody
    • V ATPase B1 subunit antibody
    • V type proton ATPase subunit B kidney isoform antibody
    • V type proton ATPase subunit B, kidney isoform antibody
    • V-ATPase subunit B 1 antibody
    • V-type proton ATPase subunit B antibody
    • Vacuolar proton pump 3 antibody
    • Vacuolar proton pump subunit 3 antibody
    • Vacuolar proton pump subunit B 1 antibody
    • VATB antibody
    • VATB1_HUMAN antibody
    • VMA2 antibody
    • Vpp 3 antibody
    • Vpp3 antibody
    see all

Anti-ATP6V1B1 antibody 图像

  • Anti-ATP6V1B1 antibody (ab98991) at 1 µg/ml + HeLa cell lysate at 10 µg

    Predicted band size : 57 kDa

Anti-ATP6V1B1 antibody (ab98991)参考文献

ab98991 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Loading amount 10 µg
Gel Running Conditions Reduced Denaturing
Sample Aedes aegypti (Mosquito) Tissue lysate - whole (Renal tubule)
Specification Renal tubule
Blocking step Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5%

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提交于 Oct 09 2014