Atipamezole hydrochloride (ab120785)

概述

  • 产品名称
    Atipamezole hydrochloride
  • 描述
    Selective α2 adrenoceptor antagonist
  • 生物学描述
    Selective α2 adrenoceptor antagonist. Ki values for receptor subtypes are 1.1 (α2A), 1.0 (α2B), 0.89 (α2C), 1300 (α1A) and 8500 nM (α1B). Centrally active following peripheral administration.
  • 纯度
    > 99%

性能

文献

This product has been referenced in:
  • Jurgens CW  et al. Alpha2A adrenergic receptor activation inhibits epileptiform activity in the rat hippocampal CA3 region. Mol Pharmacol 71:1572-81 (2007). Read more (PubMed: 17341653) »
  • Pertovaara A  et al. Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist. CNS Drug Rev 11:273-88 (2005). Read more (PubMed: 16389294) »
  • Cordi AA  et al. Potential antidepressants displayed combined alpha(2)-adrenoceptor antagonist and monoamine uptake inhibitor properties. J Med Chem 44:787-805 (2001). Read more (PubMed: 11262089) »

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