概述

  • 产品名称Anti-ATG4C抗体
    参阅全部 ATG4C 一抗
  • 描述
    小鼠多克隆抗体to ATG4C
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human ATG4C (NP_116241.2, amino acids 1-458)

  • 阳性对照
    • Human kidney tissue lysate, ATG4C transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab89417 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 52 kDa.

靶标

  • 功能Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
  • 组织特异性Highly expressed in skeletal muscle, heart, liver and testis.
  • 序列相似性Belongs to the peptidase C54 family.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • APG4 autophagy 4 homolog C (S. cerevisiae) antibody
    • APG4 autophagy 4 homolog C antibody
    • APG4 C antibody
    • APG4-C antibody
    • APG4C antibody
    • ATG 4C antibody
    • ATG4 autophagy related 4 homolog C (S. cerevisiae) antibody
    • ATG4 autophagy related 4 homolog C antibody
    • Atg4c antibody
    • ATG4C_HUMAN antibody
    • AUT (S. cerevisiae) like 1, cysteine endopeptidase antibody
    • AUT like 1, cysteine endopeptidase (S. cerevisiae) antibody
    • AUT like 1, cysteine endopeptidase antibody
    • AUT like 3 cysteine endopeptidase antibody
    • AUT-like 3 cysteine endopeptidase antibody
    • AUTL1 antibody
    • AUTL3 antibody
    • Autophagin 3 antibody
    • Autophagin-3 antibody
    • Autophagy related 4C cysteine peptidase antibody
    • Autophagy related cysteine endopeptidase 3 antibody
    • Autophagy related protein 4 homolog C antibody
    • Autophagy-related cysteine endopeptidase 3 antibody
    • Autophagy-related protein 4 homolog C antibody
    • Cysteine protease ATG4C antibody
    • EC 3.4.22 antibody
    • FLJ14867 antibody
    • OTTHUMP00000010715 antibody
    see all

Anti-ATG4C antibody 图像

  • Anti-ATG4C antibody (ab89417) at 1 µg/ml + human kidney tissue lysate at 50 µg

    Predicted band size : 52 kDa
    Observed band size : 58 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-ATG4C antibody (ab89417) at 1 µg/ml

    Lane 1 : ATG4C transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 52 kDa
    Observed band size : 52 kDa

Anti-ATG4C antibody (ab89417)参考文献

ab89417 has not yet been referenced specifically in any publications.

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