概述

  • 产品名称Anti-ATG16L1抗体
    参阅全部 ATG16L1 一抗
  • 描述
    小鼠多克隆抗体to ATG16L1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human ATG16L1 protein (NP_110430.4).

  • 阳性对照
    • Human placenta tissue lysate; ATG16L1 transfected 293T cell lysate

应用

Our Abpromise guarantee covers the use of ab90442 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 68 kDa.

靶标

  • 功能Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
  • 疾病相关Inflammatory bowel disease 10
  • 序列相似性Belongs to the WD repeat ATG16 family.
    Contains 7 WD repeats.
  • 翻译后修饰Proteolytic cleavage by activated CASP3 leads to degradation and may regulate autophagy upon cellular stress and apoptotic stimuli.
  • 细胞定位Cytoplasm. Preautophagosomal structure membrane. Recruited to omegasomes membranes by WIPI2. Omegasomes are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Localized to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5. Localizes also to discrete punctae along the ciliary axoneme.
  • Information by UniProt
  • 数据库链接
  • 形式There are 4 isoforms produced by alternative splicing.
  • 别名
    • A16L1_HUMAN antibody
    • APG16 like 1 antibody
    • APG16-like 1 antibody
    • APG16L antibody
    • APG16L beta antibody
    • ATG16 autophagy related 16 like 1 antibody
    • ATG16 autophagy related 16-like 1 (S. cerevisiae) antibody
    • ATG16A antibody
    • ATG16L antibody
    • Atg16l1 antibody
    • Autophagy related protein 16 1 antibody
    • Autophagy-related protein 16-1 antibody
    • FLJ00045 antibody
    • FLJ10035 antibody
    • FLJ10828 antibody
    • FLJ22677 antibody
    • IBD10 antibody
    • OTTHUMP00000164391 antibody
    • OTTHUMP00000164393 antibody
    • OTTHUMP00000165876 antibody
    • OTTHUMP00000165877 antibody
    • WD repeat domain 30 antibody
    • WDR30 antibody
    see all

Anti-ATG16L1 antibody 图像

  • Anti-ATG16L1 antibody (ab90442) at 1 µg/ml + Human placenta tissue lysate at 50 µg

    Predicted band size : 68 kDa
  • All lanes : Anti-ATG16L1 antibody (ab90442) at 1 µg/ml

    Lane 1 : ATG16L1 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 68 kDa

Anti-ATG16L1 antibody (ab90442)参考文献

ab90442 has not yet been referenced specifically in any publications.

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