Anti-ATAD2抗体(ab68019)

概述

  • 产品名称Anti-ATAD2抗体
    参阅全部 ATAD2 一抗
  • 描述
    小鼠多克隆抗体to ATAD2
  • 特异性This antibody is reactive against mammalian transfected lysate.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    ATAD2 (AAH19909.1, 1 a.a. ~ 362 a.a) full-length human protein.

  • 阳性对照
    • Transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab68019 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 45 kDa.

靶标

  • 功能May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.
  • 组织特异性Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors.
  • 序列相似性Belongs to the AAA ATPase family.
    Contains 1 bromo domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AAA nuclear coregulator cancer-associated protein antibody
    • AAA nuclear coregulator, cancer-associated antibody
    • ANCCA antibody
    • Atad2 antibody
    • ATAD2_HUMAN antibody
    • ATPase family AAA domain containing 2 antibody
    • ATPase family AAA domain containing protein 2 antibody
    • ATPase family AAA domain-containing protein 2 antibody
    • CT137 antibody
    • DKFZp667N1320 antibody
    • L16 antibody
    • MGC131938 antibody
    • MGC142216 antibody
    • MGC29843 antibody
    • MGC5254 antibody
    • PRO2000 antibody
    see all

Anti-ATAD2 antibody 图像

  • All lanes : Anti-ATAD2 antibody (ab68019) at 1/500 dilution

    Lane 1 : ATAD2 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 1/500 dilution per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Observed band size : 45 kDa (why is the actual band size different from the predicted?)

Anti-ATAD2 antibody (ab68019)参考文献

ab68019 has not yet been referenced specifically in any publications.

Product Wall

The antibody was raised against recombinant ATAD2, instead of overexpressed and purified protein.



The immunogen corresponds to the full length sequence found at the GenBank accession below-

http://www.ncbi.nlm.nih.gov/protein/AAH19909.1

This corresponds to the amino acids numbered 1029 to 1390 on the UniProt accession-...

Read More

Thank you for contacting us. This antibody was raised against AAH19909.1 which is a human ATAD2 sequence with an alternative initiation and therefore a lower molecular weight (~40kDa). The WB image was generated using 293T cells transfected with ...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"