概述

  • 产品名称
  • 描述
    兔多克隆抗体to ATAD2
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rabbit, Horse, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 1205-1254 (TQDTSVDHNE TGNTGESSVE ENEKQQNASE SKLELRNNSN TCNIENELED) of Human ATAD2 (NP_054828).

  • 阳性对照
    • MCF7 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab118664 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 159 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.
  • 组织特异性
    Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors.
  • 序列相似性
    Belongs to the AAA ATPase family.
    Contains 1 bromo domain.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AAA nuclear coregulator cancer-associated protein antibody
    • AAA nuclear coregulator, cancer-associated antibody
    • ANCCA antibody
    • Atad2 antibody
    • ATAD2_HUMAN antibody
    • ATPase family AAA domain containing 2 antibody
    • ATPase family AAA domain containing protein 2 antibody
    • ATPase family AAA domain-containing protein 2 antibody
    • CT137 antibody
    • DKFZp667N1320 antibody
    • L16 antibody
    • MGC131938 antibody
    • MGC142216 antibody
    • MGC29843 antibody
    • MGC5254 antibody
    • PRO2000 antibody
    see all

图片

  • Anti-ATAD2 antibody (ab118664) at 1 µg/ml + MCF7 cell lysate at 10 µg

    Predicted band size : 159 kDa

实验方案

文献

ab118664 has not yet been referenced specifically in any publications.

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