概述

  • 产品名称
    Anti-ASXL1抗体[2049C2a]
    参阅全部 ASXL1 一抗
  • 描述
    小鼠单克隆抗体[2049C2a] to ASXL1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment of ASXL1 (Human)

性能

应用

Our Abpromise guarantee covers the use of ab50817 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 165 kDa.

靶标

  • 功能
    Probable Polycomb group (PcG) protein. Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1).
  • 组织特异性
    Widely expressed at low level. Expressed in heart, brain, skeletal muscle, placenta, pancreas, spleen, prostate, small intestine, colon, peripheral blood, leukocytes, bone marrow and fetal liver. Highly expressed in testes.
  • 序列相似性
    Belongs to the Asx family.
    Contains 1 PHD-type zinc finger.
  • 结构域
    Contains one Leu-Xaa-Xaa-Leu-Leu (LXXLL) motif, which may be required for an association with nuclear receptors.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Additional sex combs like 1 (Drosophila) antibody
    • Additional sex combs like protein 1 antibody
    • Additional sex combs-like protein 1 antibody
    • ASXL1 antibody
    • ASXL1_HUMAN antibody
    • KIAA0978 antibody
    • Putative Polycomb group protein ASXL1 antibody
    see all

Anti-ASXL1 antibody [2049C2a] 图像

实验方案

Anti-ASXL1 antibody [2049C2a] (ab50817)参考文献

This product has been referenced in:
  • Balasubramani A  et al. Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex. Nat Commun 6:7307 (2015). WB ; Mouse . Read more (PubMed: 26095772) »

See 1 Publication for this product

Product Wall

I have continued to look through our catalogue and I cannot find any kits that would allow you to conjugate an antibody to Protein A/G beads. I did however find this kit which may work: Please let me know if there is anything else I can h...

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