概述

  • 产品名称Anti-Aspergillus抗体
    参阅全部 Aspergillus 一抗
  • 描述
    兔多克隆抗体to Aspergillus
  • 特异性Reactive with soluble proteins from common Aspergillus species.
  • 经测试应用适用于: ELISA, IHC-Fr, IHC-P, Conjugationmore details
  • 种属反应性
    与反应: Aspergillus nidulans
  • 免疫原

    Tissue/ cell preparation. Soluble extract from A. fumigatus, A. flavus, A. niger and A. terreus.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: 0.01M PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein A purified
  • 纯化说明>95% pure
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab20419 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.
Conjugation Use at an assay dependent concentration.

靶标

  • 相关性The genus Aspergillus includes over 185 species. Around 20 species have been reported as causative agents of opportunistic infections in humans. Among these, Aspergillus fumigatus is the most commonly isolated species, followed by Aspergillus flavus. Aspergillus fumigatus is the major cause of aspergillosis. This organism causes both invasive and allergic aspergillosis. Aspergillus also produce fungal toxins called mycotoxins. Aflatoxin is produced by Aspergillus flavus as it grows on corn and peanuts. The toxin is poisonous to humans by ingestion and causes liver disease. Aspergillus nidulans can produce the mycotoxin sterigmatocystin. This toxin has been shown to produce liver and kidney damage in lab animals. Aspergillus oschraceus,found in grains, soil and salted food products can produce a kidney toxin called oschratoxin A, which may produce oschratoxicosis in humans. Ochratoxin may also be produced by other aspergillus and penicillium species. Other toxins that can be produced by this fungus include penicillic acid, xanthomegnin and viomellein. Aspergillus infections have a very high mortality rate. Their incidence is growing because of the increased number of immunocompromised patients. Previous to antibodies such as these, special stains were used to identify aspergillus. Aspergillus oryzae and Aspergillus niger are used extensively in industrial scale fermentation to produce enzymes for processing household food and drink products.

Anti-Aspergillus antibody 图像

  • ab20419, staining Aspergillus (green) in lung tissue from a murine model of corticosteroid-induced invasive pulmonary aspergillosis, by Immunohistochemistry.

    Tissue was fixed in cold acetone for 15 min, followed by washing and blocking with normal serum block at RT for 30 min. Sections were incubated overnight at 4°C with primary antibody. An AlexaFluor®488-conjugated goat anti-rabbit IgG (1/00) was used as the secondary antibody.
  • ab20419, staining Aspergillus (green) in lung tissue from a murine model of chemotherapy-induced invasive pulmonary aspergillosis, by Immunohistochemistry.

    Tissue was fixed in cold acetone for 15 min, followed by washing and blocking with normal serum block at RT for 30 min. Sections were incubated overnight at 4°C with primary antibody. An AlexaFluor®488-conjugated goat anti-rabbit IgG (1/00) was used as the secondary antibody.

Anti-Aspergillus antibody (ab20419)参考文献

This product has been referenced in:
  • Chang SC  et al. Probable Blastomyces dermatitidis Infection in a Young Rat. Vet Pathol : (2012). Read more (PubMed: 22711744) »
  • Grahl N  et al. In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis. PLoS Pathog 7:e1002145 (2011). IHC-Fr . Read more (PubMed: 21811407) »

See all 2 Publications for this product

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Thank you for contacting us. Sorry for the delay.

It seems that one of your colleague is already in contact with us. We have provided all the information we have regarding this product. I am sorry we do not have any additional information.
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Gracias por tu paciencia.

Me confirman mis compañeros del laboratorio que el extracto soluble usado como inmunógeno de este anticuerpo es una mezcla de esporas e hifa procedentes de A. fumigatus, A. flavus, A. niger and A. terre...

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Gracias por contactar con Abcam.

Mi compañera no se encuentra hoy en la oficina.

Thank you for your inquiry.

The antibody you mentioned is a polyclonal antibody. Polyclonal antibodies consist of a mixed population ...

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I am sorry for the delay in getting back to you with the ELISA protocol information for the Anti-Aspergillus antibody (ab20419). I now have further information to share with you. The antibody has been used as follows:

1. Coat plate with a com...

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Thank you for your enquiry. Unfortunately, we have no antibodies I can recommend that will specifically detect intact aspergillus spores. However, I can offer the following information regarding the antibodies you have suggested: In immunofluor...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"