概述

  • 产品名称
  • 描述
    山羊多克隆抗体to ASNA1
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Cow, Zebrafish
  • 免疫原

    Synthetic peptide:

    C-PHEVRGADKVNT

    , corresponding to internal sequence amino acids 322-333 of Human ASNA1 (NP_004308.2)

  • 阳性对照
    • Human, Mouse and Rat Kidney lysates

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab81979 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab81979 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明
    Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution 1/2,000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling.
    • 组织特异性
      Expressed in the epithelial cells of the liver, kidney, and stomach wall, in the adrenal medulla, in the islet cells of the pancreas, in the red pulp of the spleen, and in cardiac and skeletal muscle.
    • 序列相似性
      Belongs to the arsA ATPase family.
    • 细胞定位
      Cytoplasm. Endoplasmic reticulum. Nucleus > nucleolus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ARSA 1 antibody
      • ARSA antibody
      • ArsA arsenite transporter ATP binding homolog 1 antibody
      • ArsA arsenite transporter, ATP binding, E. coli, homolog of, 1 antibody
      • ArsA arsenite transporter, ATP-binding, homolog 1 (bacterial) antibody
      • ARSA I antibody
      • ARSA-I antibody
      • ARSA1 antibody
      • ARSAI antibody
      • Arsenical pump driving ATPase antibody
      • Arsenical pump-driving ATPase antibody
      • Arsenical resistance ATPase antibody
      • Arsenite translocating ATPase antibody
      • Arsenite transporting ATPase antibody
      • Arsenite-stimulated ATPase antibody
      • ASNA 1 antibody
      • ASNA I antibody
      • ASNA-I antibody
      • ASNA_HUMAN antibody
      • ASNA1 antibody
      • Asna1 protein antibody
      • ASNAI antibody
      • ATPase ASNA1 antibody
      • GET3 antibody
      • Golgi to ER traffic 3 homolog antibody
      • hARSA-I antibody
      • hASNA-I antibody
      • MGC3821 antibody
      • Transmembrane domain recognition complex 40 kDa ATPase subunit antibody
      • Transmembrane domain recognition complex, 40kDa antibody
      • TRC40 antibody
      see all

    Anti-ASNA1 antibody 图像

    • Anti-ASNA1 antibody (ab81979) at 1 µg/ml + Mouse Kidney lysate at 35 µg

      Predicted band size : 39 kDa
      Observed band size : 39 kDa

    实验方案

    Anti-ASNA1 antibody (ab81979)参考文献

    ab81979 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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