概述

  • 产品名称Anti-ASNA1抗体
    参阅全部 ASNA1 一抗
  • 描述
    小鼠单克隆抗体to ASNA1
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 239-349 of Human ASNA1

性能

应用

Our Abpromise guarantee covers the use of ab54843 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 39 kDa.
IHC-P Use a concentration of 5 µg/ml.
ICC/IF Use a concentration of 10 µg/ml.

靶标

  • 功能ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling.
  • 组织特异性Expressed in the epithelial cells of the liver, kidney, and stomach wall, in the adrenal medulla, in the islet cells of the pancreas, in the red pulp of the spleen, and in cardiac and skeletal muscle.
  • 序列相似性Belongs to the arsA ATPase family.
  • 细胞定位Cytoplasm. Endoplasmic reticulum. Nucleus > nucleolus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ARSA 1 antibody
    • ARSA antibody
    • ArsA arsenite transporter ATP binding homolog 1 antibody
    • ArsA arsenite transporter, ATP binding, E. coli, homolog of, 1 antibody
    • ArsA arsenite transporter, ATP-binding, homolog 1 (bacterial) antibody
    • ARSA I antibody
    • ARSA-I antibody
    • ARSA1 antibody
    • ARSAI antibody
    • Arsenical pump driving ATPase antibody
    • Arsenical pump-driving ATPase antibody
    • Arsenical resistance ATPase antibody
    • Arsenite translocating ATPase antibody
    • Arsenite transporting ATPase antibody
    • Arsenite-stimulated ATPase antibody
    • ASNA 1 antibody
    • ASNA I antibody
    • ASNA-I antibody
    • ASNA_HUMAN antibody
    • ASNA1 antibody
    • Asna1 protein antibody
    • ASNAI antibody
    • ATPase ASNA1 antibody
    • GET3 antibody
    • Golgi to ER traffic 3 homolog antibody
    • hARSA-I antibody
    • hASNA-I antibody
    • MGC3821 antibody
    • Transmembrane domain recognition complex 40 kDa ATPase subunit antibody
    • Transmembrane domain recognition complex, 40kDa antibody
    • TRC40 antibody
    see all

Anti-ASNA1 antibody 图像

  • ASNA1 antibody (ab54843) used in immunohistochemistry at 5ug/ml on formalin fixed and paraffin embedded human testis.


  • Predicted band size : 39 kDa
    ASNA1 antibody (ab54843) at 1ug/lane + HeLa cell lysate at 25ug/lane.
  • ab54843 at 10 ug/ml staining in human Hela cells by Immunocytochemistry / Immunofluorescence.

Anti-ASNA1 antibody (ab54843)参考文献

ab54843 has not yet been referenced specifically in any publications.

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