Anti-ASK1 (phospho S83)抗体- Azide free (ab14380)

概述

  • 产品名称Anti-ASK1 (phospho S83)抗体- Azide free
    参阅全部 ASK1 一抗
  • 描述
    兔多克隆抗体to ASK1 (phospho S83) - Azide free
  • 特异性Detects overexpressed ASK1 only when phosphorylated at Ser83.
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (Human)corresponding to residues around Ser83 of human ASK1 conjugated to KLH.

性能

应用

Our Abpromise guarantee covers the use of ab14380 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 155 kDa.
IP 1/100.

靶标

  • 功能Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.
  • 组织特异性Abundantly expressed in heart and pancreas.
  • 序列相似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    Contains 1 protein kinase domain.
  • 翻译后修饰Dephosphorylated and activated by PGAM5.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Apoptosis signal regulating kinase 1 antibody
    • Apoptosis signal-regulating kinase 1 antibody
    • ASK 1 antibody
    • ASK-1 antibody
    • ASK1 antibody
    • M3K5 antibody
    • M3K5_HUMAN antibody
    • MAP/ERK kinase kinase 5 antibody
    • MAP3K5 antibody
    • MAPK/ERK kinase kinase 5 antibody
    • MAPKKK5 antibody
    • MEK kinase 5 antibody
    • MEKK 5 antibody
    • MEKK5 antibody
    • Mitogen activated protein kinase kinase kinase 5 antibody
    • Mitogen-activated protein kinase kinase kinase 5 antibody
    see all

Anti-ASK1 (phospho S83) antibody - Azide free (ab14380)参考文献

ab14380 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your email. Regarding ab14380, I double-checked with the source of this antibody and we do believe that the antibody will not be able to detect endogenous ASK1. As stated on the datasheet, "Detects overexpressed ASK1 only when phosphoryla...

Read More

Thank you for your enquiry. Ab14380 detects overexpressed ASK1 only when phosphorylated at Ser83. Ab5689 - a band of 155 kDa was detected using SW1353 whole cell lysate. If you have any additional questions, please contact us again.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"