Anti-Asialoglycoprotein Receptor 2抗体(ab37470)

概述

  • 产品名称Anti-Asialoglycoprotein Receptor 2抗体
    参阅全部 Asialoglycoprotein Receptor 2 一抗
  • 描述
    兔多克隆抗体to Asialoglycoprotein Receptor 2
  • 特异性Ab37470 detects all three isoforms of Asialoglycoprotein Receptor.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (Human)

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab37470 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 4 µg/ml. Predicted molecular weight: 35 kDa.

靶标

  • 功能Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
  • 组织特异性Expressed exclusively in hepatic parenchymal cells.
  • 序列相似性Contains 1 C-type lectin domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ASGP R antibody
    • ASGP-R 2 antibody
    • ASGPR 2 antibody
    • ASGPR2 antibody
    • Asgr2 antibody
    • ASGR2_HUMAN antibody
    • Asialoglycoprotein receptor 2 antibody
    • C type lectin domain family 4 member H2 antibody
    • C-type lectin domain family 4 member H2 antibody
    • CLEC4H2 antibody
    • HBxAg-binding protein antibody
    • HBXBP antibody
    • Hepatic lectin 2 antibody
    • Hepatic lectin H2 antibody
    • Hepatic lectin R2/3 antibody
    • HL-2 antibody
    • Hs.1259 antibody
    • L H2 antibody
    • LH2 antibody
    • MGC108546 antibody
    • MHL 2 antibody
    • RHL2 antibody
    see all

Anti-Asialoglycoprotein Receptor 2 antibody (ab37470)参考文献

This product has been referenced in:
  • Speicher T  et al. Knockdown and knockout of ß1-integrin in hepatocytes impairs liver regeneration through inhibition of growth factor signalling. Nat Commun 5:3862 (2014). Read more (PubMed: 24844558) »

See 1 Publication for this product

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Abcam has not validated the combination of species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (HepG2)
Specification HepG2
Fixative Paraformaldehyde
Permeabilization No
Blocking step Protein Block (serum free) as blocking agent for 20 minute(s) · Concentration: 100% · Temperature: 4°C
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Abcam user community

Verified customer

提交于 Oct 08 2008

Thank you for your enquiry and patience while I researched your inquiry. ab37470 will detect all three isoforms of Asialoglycoprotein Rec. 2. I have updated the datasheet to reflect this. To date this antibody has only been tested for application b...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"