概述

  • 产品名称Anti-ASH2L抗体
    参阅全部 ASH2L 一抗
  • 描述
    兔多克隆抗体to ASH2L
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Horse, Chicken, Guinea pig, Cow, Dog, Turkey, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Platypus (Ornithorhynchus anatinus)
  • 免疫原

    Synthetic peptide corresponding to a region between C terminal residues 575 and 628 of Human ASH2L (SwissProt entry: Q9UBL3). Note: the amino acid sequence is considered to be commercially sensitive.

  • 阳性对照
    • Human ovarian carcinoma; Mouse squamous cell carcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab84407 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500. Antigen retrieval with citrate buffer will enhance staining.
    Note: expected to work on frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
    • 组织特异性Ubiquitously expressed. Predominantly expressed in adult heart and testis and fetal lung and liver, with barely detectable expression in adult lung, liver, kidney, prostate, and peripheral leukocytes.
    • 序列相似性Contains 1 B30.2/SPRY domain.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ASH 2 antibody
      • Ash2 (absent small or homeotic) like antibody
      • Ash2 (absent, small, or homeotic) like (Drosophila) antibody
      • ASH2 antibody
      • ASH2 LIKE antibody
      • ASH2 like protein antibody
      • ASH2-like protein antibody
      • Ash2l antibody
      • ASH2L_HUMAN antibody
      • ASH2L1 antibody
      • ASH2L2 antibody
      • Bre 2 antibody
      • Bre2 antibody
      • Discs 2-like antibody
      • Drosophila absent, small, or homeotic antibody
      • Drosophila ASH2-like antibody
      • Set1/Ash2 histone methyltransferase complex subunit ASH2 antibody
      see all

    Anti-ASH2L antibody 图像

    • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human ovarian carcinoma, using 1/250 ab84407 followed by DAB staining.
    • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Mouse squamous cell carcinoma, using 1/250 ab84407 followed by DAB staining.

    Anti-ASH2L antibody (ab84407)参考文献

    ab84407 has not yet been referenced specifically in any publications.

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