概述

  • 产品名称Anti-ASF1a抗体
    参阅全部 ASF1A 一抗
  • 描述
    兔多克隆抗体to ASF1a
  • 特异性This antibody may cross-react with ASF1 beta.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide: SNPRVTRFH INWEDNTEKL EDAESSNPN L, corresponding to internal sequence amino acids 141-170 of Human ASF1a

  • 阳性对照
    • Jurkat cell extract

性能

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应用

Our Abpromise guarantee covers the use of ab69935 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 23 kDa (predicted molecular weight: 23 kDa).
ELISA 1/20000.

靶标

  • 功能Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
  • 组织特异性Ubiquitously expressed.
  • 序列相似性Belongs to the ASF1 family.
  • 翻译后修饰Phosphorylated by TLK1 and TLK2. Highly phosphorylated in S-phase and at lower levels in M-phase.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Anti silencing function 1A antibody
    • Anti-silencing function protein 1 homolog A antibody
    • ASF1 anti silencing function 1 homolog A (S. cerevisiae) antibody
    • ASF1 anti silencing function 1 homolog A antibody
    • asf1a antibody
    • ASF1A_HUMAN antibody
    • CCG1 interacting factor A antibody
    • CCG1-interacting factor A antibody
    • CGI 98 antibody
    • CIA antibody
    • hAsf1 antibody
    • hAsf1a antibody
    • hCIA antibody
    • Histone chaperone ASF1A antibody
    • HSPC146 antibody
    see all

Anti-ASF1a antibody 图像

  • All lanes : Anti-ASF1a antibody (ab69935) at 1/500 dilution

    Lane 1 : Jurkat cell extract
    Lane 2 : Jurkat cell extract with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 23 kDa
    Observed band size : 23 kDa

Anti-ASF1a antibody (ab69935)参考文献

ab69935 has not yet been referenced specifically in any publications.

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