概述

  • 产品名称
  • 描述
    兔多克隆抗体to ASC-2
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Horse, Guinea pig, Dog, Chimpanzee, Rhesus monkey, Gorilla, Bat, Elephant
  • 免疫原

    Synthetic peptide, corresponding to a region within the C terminal amino acids 2000-2063 of Human ASC-2 (SwissProt: Q14686).

  • 阳性对照
    • Human breast adenocarcinoma. Human stomach adenocarcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab84099 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明
    IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.
    Likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性
      The protein encoded by this gene is a nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone dependent fashion. It is involved in the coactivation of different nuclear receptors, such as steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). It probably functions as a general coactivator, rather than just a nuclear receptor coactivator,and may also be involved in the coactivation of the NFkB pathway (referenced from swissprot).
    • 细胞定位
      Nuclear
    • 数据库链接
    • 别名
      • Activating signal cointegrator 2 antibody
      • AIB3 antibody
      • Amplified in breast cancer 3 protein antibody
      • Cancer amplified transcriptional coactivator ASC 2 antibody
      • NCOA6 antibody
      • Nuclear receptor coactivator 6 antibody
      • Nuclear receptor coactivator RAP250 antibody
      • PPAR interacting protein antibody
      • Thyroid hormone receptor binding protein antibody
      see all

    图片

    • Detection of Human ASC-2 by Immunohistochemistry.
      Sample: FFPE section of Human breast adenocarcinoma.
      Antibody: ab84099 used at a dilution of 1/100.
      Detection: DAB.
    • Detection of Human ASC-2 by Immunohistochemistry.
      Sample: FFPE section of Human stomach adenocarcinoma.
      Antibody: ab84099 used at a dilution of 1/100.
      Detection: DAB.

    文献

    ab84099 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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