概述

  • 产品名称Anti-ASB8抗体
    参阅全部 ASB8 一抗
  • 描述
    小鼠单克隆抗体to ASB8
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 179-289 of Human ASB8 (NP_077000) with a proprietary tag.

  • 阳性对照
    • Recombinant Protein. Human pancreas tissue.

性能

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应用

Our Abpromise guarantee covers the use of ab118338 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 3 µg/ml. Do not perform antigen retrieval. Place sample in 1X citrate buffer (pH 6.0) in pressure cooker under 125 °C for 4min and under 90 °C for 45min, cool sample subsequently.

靶标

  • 功能May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
  • 组织特异性Highest level of expression in skeletal muscle. Also expressed in heart, brain, placenta, liver, kidney and pancreas.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Contains 4 ANK repeats.
    Contains 1 SOCS box domain.
  • 结构域The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Ankyrin repeat and SOCS box containing 8 antibody
    • Ankyrin repeat and SOCS box protein 8 antibody
    • ASB 8 antibody
    • ASB-8 antibody
    • ASB8 antibody
    • ASB8_HUMAN antibody
    • FLJ21255 antibody
    • MGC5540 antibody
    • OTTHUMP00000237000 antibody
    • OTTHUMP00000237001 antibody
    • OTTHUMP00000237007 antibody
    • OTTHUMP00000237009 antibody
    • OTTHUMP00000237010 antibody
    • PP14212 antibody
    see all

Anti-ASB8 antibody 图像

  • ab118338 at 3 µg/ml staining ASB8 in Formalin-Fixed, Paraffin-Embedded Human Pancreas tissue by Immunohistochemistry.

Anti-ASB8 antibody (ab118338)参考文献

ab118338 has not yet been referenced specifically in any publications.

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