Recombinant fragment, corresponding to a region within amino acids 29-327 of Human ASB4 isoform CRA_c (NP_665879).
293T, H1299, HeLaS3, HepG2, Molt-4, Raji cell lysates and A431 whole cell lysate.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.01M Tris, 0.01M Glycine, pH 7
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 39 kDa.
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Protein modification; protein ubiquitination.
Contains 6 ANK repeats.
Contains 1 SOCS box domain.
The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes.
Information by UniProt
Ankyrin repeat and SOCS box containing 4 antibody
Ankyrin repeat and SOCS box containing protein 4 antibody
Ankyrin repeat and SOCS box protein 4 antibody
has not yet been referenced specifically in any publications.
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