概述

  • 产品名称Anti-ASB13抗体
    参阅全部 ASB13 一抗
  • 描述
    小鼠单克隆抗体to ASB13
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: AGAQVDARNI DGSTPLCDAC ASGSIECVKL LLSYGAKVNP PLYTASPLHE ACMSGSSECV RLLIDVGANL EAHDCHFGTP LHVACAREHL DCVKVLLNAA , corresponding to amino acids 74-174 of Human ASB13

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab57777 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
    • 通路Protein modification; protein ubiquitination.
    • 序列相似性Contains 6 ANK repeats.
      Contains 1 SOCS box domain.
    • 结构域The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Ankyrin repeat and SOCS box containing 13 antibody
      • Ankyrin repeat and SOCS box containing protein 13 antibody
      • Ankyrin repeat and SOCS box protein 13 antibody
      • Ankyrin repeat domain containing SOCS box protein Asb 13 antibody
      • Ankyrin repeat domain containing SOCS box protein Asb13 antibody
      • ASB 13 antibody
      • ASB-13 antibody
      • Asb13 antibody
      • ASB13_HUMAN antibody
      • FLJ13134 antibody
      • MGC19879 antibody
      see all

    Anti-ASB13 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57777 ASB13 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-ASB13 antibody (ab57777)参考文献

    This product has been referenced in:
    • Zhang Y  et al. miR-125b Is Methylated and Functions as a Tumor Suppressor by Regulating the ETS1 Proto-oncogene in Human Invasive Breast Cancer. Cancer Res 71:3552-62 (2011). WB ; Human . Read more (PubMed: 21444677) »

    See 1 Publication for this product

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