概述

  • 产品名称Anti-ASAHL抗体
    参阅全部 ASAHL 一抗
  • 描述
    小鼠单克隆抗体to ASAHL
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Recombinant fragment: FNVSLDSVPE LRWLPVLRHY DLDLVRAAMA QVIGDRVPKW VHVLIGKVVL ELERFLPQPF TGEIRGMCD, corresponding to amino acids 36-105 of Human ASAHL

性能

应用

Our Abpromise guarantee covers the use of ab57123 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N-palmitoylethanolamine > N-myristoylethanolamine > N-lauroylethanolamine = N-stearoylethanolamine > N-arachidonoylethanolamine > N-oleoylethanolamine. Also exhibits weak hydrolytic activity against the ceramides N-lauroylsphingosine and N-palmitoylsphingosine.
    • 组织特异性Expressed in numerous tissues, with highest levels in liver and kidney, followed by pancreas.
    • 序列相似性Belongs to the acid ceramidase family.
    • 翻译后修饰N-glycosylated. Tunicamycin treatment causes a reduction in specific activity against N-palmitoylethanolamine.
      Autoproteolytic cleavage in the acidic lumen of the lysosome activates the enzyme.
    • 细胞定位Lysosome.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Acid ceramidase like protein antibody
      • Acid ceramidase-like protein antibody
      • ASAH like protein antibody
      • ASAH-like protein antibody
      • N acylethanolamine acid amidase antibody
      • N acylethanolamine hydrolyzing acid amidase antibody
      • N acylsphingosine amidohydrolase (acid ceramidase) like antibody
      • N acylsphingosine amidohydrolase like antibody
      • N acylsphingosine amidohydrolase like protein antibody
      • N-acylethanolamine-hydrolyzing acid amidase subunit beta antibody
      • N-acylsphingosine amidohydrolase-like antibody
      • Naaa antibody
      • NAAA_HUMAN antibody
      • PLT antibody
      see all

    Anti-ASAHL antibody 图像



    • Predicted band size : 40 kDa
      ASAHL antibody (ab57123) at 1ug/lane + NIH/3T3 cell lysate at 25ug/lane.

    Anti-ASAHL antibody (ab57123)参考文献

    ab57123 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"