概述

  • 产品名称Anti-Artemin抗体
    参阅全部 Artemin 一抗
  • 描述
    山羊多克隆抗体to Artemin
  • 特异性ab109812 is expected to recognize all reported isoforms (NP_003967.2; NP_476501.1; NP_476431.2). Reported variants represent identical protein: NP_476431.2, NP_001129687.1 Reported variants represent identical protein: NP_003967.2, NP_476432.2.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Synthetic peptide:

    C-NSTWRTVDRLS

    , corresponding to internal sequence amino acids 202-212 of Human Artemin (NP_003967.2) amino acids 210-220 (NP_476431.2) or amino acids 219-229 (NP_476501.1).

  • 阳性对照
    • HEK293, HepG2 and Kelly cell lysates.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab109812 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab109812 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 23 kDa.

靶标

  • 功能Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain.
  • 组织特异性Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain.
  • 序列相似性Belongs to the TGF-beta family. GDNF subfamily.
  • 发展阶段Expressed during embryogenesis. High level expression seen in fetal kidney and lung while a low level expression seen in the fetal brain.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Artemin antibody
    • Artn antibody
    • ARTN_HUMAN antibody
    • Enovin antibody
    • EVN antibody
    • NBN antibody
    • Neublastin antibody
    • Neurotrophic factor antibody
    see all

Anti-Artemin antibody 图像

  • Anti-Artemin antibody (ab109812) at 0.1 µg/ml + HEK293 lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 23 kDa

Anti-Artemin antibody (ab109812)参考文献

ab109812 has not yet been referenced specifically in any publications.

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