概述

  • 产品名称
  • 描述
    兔多克隆抗体to ARS2
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Recombinant fragment
    预测可用于: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to C terminal residues of human ARS2.

性能

应用

Our Abpromise guarantee covers the use of ab55822 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 101 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.

靶标

  • 功能
    Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity.
  • 组织特异性
    Ubiquitously expressed.
  • 序列相似性
    Belongs to the ARS2 family.
  • 细胞定位
    Nucleus > nucleoplasm. Cytoplasm. Predominantly nuclear. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent way.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ARS2 protein antibody
    • Arsenate resistance protein ARS2 antibody
    • Arsenite resistance protein 2 antibody
    • Arsenite resistance protein antibody
    • Arsenite-resistance protein 2 antibody
    • ASR2 antibody
    • MGC126427 antibody
    • Serrate antibody
    • Serrate RNA effector molecule antibody
    • Serrate RNA effector molecule homolog (Arabidopsis) antibody
    • Serrate RNA effector molecule homolog antibody
    • SRRT antibody
    • SRRT_HUMAN antibody
    see all

实验方案

文献

ab55822 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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