概述

  • 产品名称
  • 描述
    山羊多克隆抗体to ARMET
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Dog
  • 免疫原

    Synthetic peptide:

    KFCREARGKENR

    , corresponding to internal sequence amino acids 59-70 of Human ARMET (vNP_006001.2).

  • 阳性对照
    • Human pancreas lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab77267 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab77267 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明
    Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution 1/16,000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 20 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
    • 序列相似性
      Belongs to the ARMET family.
    • 结构域
      The N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response.
    • 翻译后修饰
      May contain sialic acid residues.
    • 细胞定位
      Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Arginine rich mutated in early stage tumors antibody
      • Arginine rich protein antibody
      • Arginine-rich protein antibody
      • ARMET antibody
      • ARMET protein antibody
      • ARP antibody
      • Manf antibody
      • MANF_HUMAN antibody
      • Mesencephalic astrocyte derived neurotrophic factor antibody
      • Mesencephalic astrocyte-derived neurotrophic factor antibody
      • MGC142148 antibody
      • MGC142150 antibody
      • Protein ARMET antibody
      see all

    图片

    • Anti-ARMET antibody (ab77267) at 0.3 µg/ml + Human Pancreas lysate (in RIPA buffer) at 35 µg

      Predicted band size : 20 kDa
      Observed band size : 20 kDa

    实验方案

    文献

    ab77267 has not yet been referenced specifically in any publications.

    客户评价及客户问答

    There are currently no Customer reviews or Questions for ab77267.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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