概述

  • 产品名称Anti-ARMET抗体
    参阅全部 ARMET 一抗
  • 描述
    兔多克隆抗体to ARMET
  • 经测试应用适用于: WB, ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    12 amino acid peptide from near the amino terminus of human MANF.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Purified IgA
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab67203 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 20 kDa).
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use a concentration of 2.5 µg/ml.

靶标

  • 功能Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
  • 序列相似性Belongs to the ARMET family.
  • 结构域The N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response.
  • 翻译后修饰May contain sialic acid residues.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Arginine rich mutated in early stage tumors antibody
    • Arginine rich protein antibody
    • Arginine-rich protein antibody
    • ARMET antibody
    • ARMET protein antibody
    • ARP antibody
    • Manf antibody
    • MANF_HUMAN antibody
    • Mesencephalic astrocyte derived neurotrophic factor antibody
    • Mesencephalic astrocyte-derived neurotrophic factor antibody
    • MGC142148 antibody
    • MGC142150 antibody
    • Protein ARMET antibody
    see all

Anti-ARMET antibody 图像

  • Lane 1 : Anti-ARMET antibody (ab67203) at 1 µg/ml
    Lane 2 : Anti-ARMET antibody (ab67203) at 2 µg/ml

    Lane 1 : rat brain tissue lysate
    Lane 2 : rat brain tissue lysate


    Predicted band size : 20 kDa
  • Ab67203 (2.5 ug/ml) staining of ARMET in human brain tissue by IHC.
  • Immunofluorescence of MANF in Human Brain cells using ab67203 at 20 ug/ml.

Anti-ARMET antibody (ab67203)参考文献

This product has been referenced in:
  • Di Penta A  et al. A trifluoromethyl analogue of celecoxib exerts beneficial effects in neuroinflammation. PLoS One 8:e83119 (2013). WB ; Mouse . Read more (PubMed: 24349442) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"