概述

  • 产品名称Anti-ARHGEF9抗体
    参阅全部 ARHGEF9 一抗
  • 描述
    兔多克隆抗体to ARHGEF9
  • 经测试应用适用于: ELISA, WB, IHC-Pmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids of Rat ARHGEF9.

  • 阳性对照
    • Rat Brain, Purkinje tissue.

性能

应用

Our Abpromise guarantee covers the use of ab118494 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/50 - 1/100. Predicted molecular weight: 58 kDa.
IHC-P Use a concentration of 10 µg/ml.

靶标

  • 功能Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
  • 组织特异性Detected in brain. Detected at low levels in heart.
  • 疾病相关Defects in ARHGEF9 are a cause of startle disease with epilepsy (STHEE) [MIM:300607]; also known as hyperekplexia with epilepsy. Startle disease is a genetically heterogeneous neurologic disorder. STHE is characterized by muscular rigidity of central nervous system origin, particularly in the neonatal period, and by an exaggerated startle response to unexpected acoustic or tactile stimuli.
  • 序列相似性Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
    Contains 1 SH3 domain.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 9630036L12Rik antibody
    • A230067K14 antibody
    • ARHG9_HUMAN antibody
    • Arhgef9 antibody
    • Cdc42 guanine nucleotide exchange factor (GEF) 9 antibody
    • Collybistin antibody
    • collybistin I antibody
    • EIEE8 antibody
    • HPEM 2 antibody
    • hPEM-2 collybistin antibody
    • KIAA0424 antibody
    • mKIAA0424 antibody
    • OTTHUMP00000023424 antibody
    • OTTHUMP00000023425 antibody
    • OTTHUMP00000023427 antibody
    • PEM 2 antibody
    • PEM 2 homolog antibody
    • PEM-2 homolog antibody
    • PEM2 antibody
    • Rac/Cdc42 guanine nucleotide exchange factor 9 antibody
    • Rho guanine nucleotide exchange factor 9 antibody
    • RP11 357C3.4 antibody
    • RP23 230K20.3 antibody
    see all

Anti-ARHGEF9 antibody 图像

  • ab118494 at 10 µg/ml staining ARHGEF9 in Formalin-fixed, Paraffin-embedded Rat Purkinje tissue by Immunohistochemistry.

Anti-ARHGEF9 antibody (ab118494)参考文献

ab118494 has not yet been referenced specifically in any publications.

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