概述

  • 产品名称Anti-ARHGEF6抗体
    参阅全部 ARHGEF6 一抗
  • 描述
    兔多克隆抗体to ARHGEF6
  • 经测试应用适用于: IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Gorilla
  • 免疫原

    Synthetic peptide, corresponding to a region between residues 726 and 776 of Human ARHGEF6 (NP_004831.1).

  • 阳性对照
    • Jurkat whole cell lysates

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: Tris citrate/phosphate, pH 7-8
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab91572 was affinity purified using an epitope specific to ARHGEF6 immobilized on solid support.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab91572 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP
  • 应用说明IP: Use at 5-15 µg/mg of lysate.

    Is unsuitable for WB.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Acts as a RAC1 guanine nucleotide exchange factor (GEF).
    • 组织特异性Ubiquitous.
    • 疾病相关Defects in ARHGEF6 are the cause of mental retardation X-linked type 46 (MRX46) [MIM:300436]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
    • 序列相似性Contains 1 CH (calponin-homology) domain.
      Contains 1 DH (DBL-homology) domain.
      Contains 1 PH domain.
      Contains 1 SH3 domain.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Alpha Pix antibody
      • Alpha-Pix antibody
      • ARHG6_HUMAN antibody
      • ARHGEF6 antibody
      • COOL 2 antibody
      • COOL-2 antibody
      • COOL2 antibody
      • Mental retardation, X linked 46 antibody
      • MRX46 antibody
      • PAK interacting exchange factor alpha antibody
      • PAK-interacting exchange factor alpha antibody
      • PIXA antibody
      • Rac/Cdc42 guanine exchange factor (GEF) 6 antibody
      • Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 antibody
      • Rac/Cdc42 guanine nucleotide exchange factor 6 antibody
      • Rho guanine nucleotide exchange factor 6 antibody
      see all

    Anti-ARHGEF6 antibody 图像

    • Detection of ARHGEF6 by Western Blot of Immunprecipitate.
      anti-ARHGEF6, at 1 µg/ml, staining ARHGEF6 in Jurkat whole cell lysate immunoprecipitated using ab91572 at 10 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
      Detection: Chemiluminescence with exposure time of 10 seconds.

    Anti-ARHGEF6 antibody (ab91572)参考文献

    ab91572 has not yet been referenced specifically in any publications.

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