概述

  • 产品名称Anti-ARHGEF6抗体
    参阅全部 ARHGEF6 一抗
  • 描述
    兔多克隆抗体to ARHGEF6
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region within the internal sequence amino acids 50-100 (PGSVEKFCLD PQTEADCINN INDFLKGCAT LQVEIFDPDD LYSGVNFSKV L) of Human ARHGEF6 (NP_004831.1).

  • 阳性对照
    • Jurkat whole cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: Tris citrate/phosphate, pH 7-8
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Antibody was affinity purified using an epitope specific to ARHGEF6 immobilized on solid support.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab91562 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IP
  • 应用说明IP: Use at 5-15µg/mg of lysate.
    WB: 1/2000 - 1/10000. Predicted molecular weight: 87 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Acts as a RAC1 guanine nucleotide exchange factor (GEF).
    • 组织特异性Ubiquitous.
    • 疾病相关Defects in ARHGEF6 are the cause of mental retardation X-linked type 46 (MRX46) [MIM:300436]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
    • 序列相似性Contains 1 CH (calponin-homology) domain.
      Contains 1 DH (DBL-homology) domain.
      Contains 1 PH domain.
      Contains 1 SH3 domain.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Alpha Pix antibody
      • Alpha-Pix antibody
      • ARHG6_HUMAN antibody
      • ARHGEF6 antibody
      • COOL 2 antibody
      • COOL-2 antibody
      • COOL2 antibody
      • Mental retardation, X linked 46 antibody
      • MRX46 antibody
      • PAK interacting exchange factor alpha antibody
      • PAK-interacting exchange factor alpha antibody
      • PIXA antibody
      • Rac/Cdc42 guanine exchange factor (GEF) 6 antibody
      • Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 antibody
      • Rac/Cdc42 guanine nucleotide exchange factor 6 antibody
      • Rho guanine nucleotide exchange factor 6 antibody
      see all

    Anti-ARHGEF6 antibody 图像

    • ab91562 at 1 µg/ml detecting ARHGEF6 in Jurkat whole cell lysate by WB following IP. Lane 1; IP with ab91562 at 10 µg/mg of lysate. Lane 2; IP with an antibody which recognizes an downstream epitope of ARHGEF6. Lane 3; control IgG. In each case, 1 mg of lysate was used for IP and 20% of the IP was loaded. Detection utilised ECL with a 10 second exposure.
    • All lanes : Anti-ARHGEF6 antibody (ab91562) at 0.1 µg/ml

      Lane 1 : Jurkat whole cell lysate at 50 µg
      Lane 2 : Jurkat whole cell lysate at 15 µg
      Lane 3 : Jurkat whole cell lysate at 5 µg

      Developed using the ECL technique

      Predicted band size : 87 kDa


      Exposure time : 3 minutes

    Anti-ARHGEF6 antibody (ab91562)参考文献

    ab91562 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab91562.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"