概述

  • 产品名称Anti-ARHGEF14抗体
    参阅全部 ARHGEF14 一抗
  • 描述
    兔多克隆抗体to ARHGEF14
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 54-307 of Human ARHGEF14 (NP_001106203).

  • 阳性对照
    • Molt-4 and Raji whole cell lysates; 293T, A431, H1299, HeLa and HepG2 cell lysates

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab96395 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 128 kDa.

靶标

  • 功能Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.
  • 序列相似性Belongs to the MCF2 family.
    Contains 1 CRAL-TRIO domain.
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
    Contains 1 SH3 domain.
    Contains 1 spectrin repeat.
  • 结构域The CRAL-TRIO domain is involved in interaction with inositol phospholipids.
    The DH domain is involved in interaction with CCPG1.
  • 细胞定位Cytoplasm. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ARHGEF 14 antibody
    • DBL''s big sister antibody
    • DBS antibody
    • FLJ12122 antibody
    • Guanine nucleotide exchange factor DBS antibody
    • KIAA0362 antibody
    • MCF 2L antibody
    • MCF.2 cell line derived transforming sequence like antibody
    • MCF.2 transforming sequence-like antibody
    • MCF2 like protein antibody
    • MCF2 transforming sequence like protein antibody
    • MCF2-transforming sequence-like protein antibody
    • Mcf2l antibody
    • MCF2L_HUMAN antibody
    • OST antibody
    • OST oncogene antibody
    see all

Anti-ARHGEF14 antibody 图像

  • All lanes : Anti-ARHGEF14 antibody (ab96395) at 1/1000 dilution

    Lane 1 : Molt-4 whole cell lysate
    Lane 2 : Raji whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 128 kDa

Anti-ARHGEF14 antibody (ab96395)参考文献

ab96395 has not yet been referenced specifically in any publications.

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