概述

  • 产品名称Anti-ARHGEF11抗体
    参阅全部 ARHGEF11 一抗
  • 描述
    兔多克隆抗体to ARHGEF11
  • 特异性This antibody detects endogenous levels of total ARHGEF11 protein.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from the N terminal region of Human ARHGEF11.

  • 阳性对照
    • A549 and COLO cell extracts.

性能

应用

Our Abpromise guarantee covers the use of ab110059 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 168 kDa.

靶标

  • 功能May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.
  • 组织特异性Ubiquitously expressed.
  • 序列相似性Contains 1 DH (DBL-homology) domain.
    Contains 1 PDZ (DHR) domain.
    Contains 1 PH domain.
    Contains 1 RGSL (RGS-like) domain.
  • 结构域The poly-Pro region is essential for plasma membrane localization upon stimulation.
  • 细胞定位Cytoplasm. Membrane. Translocated to the membrane upon stimulation.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ARHGB_HUMAN antibody
    • ARHGEF 11 antibody
    • ARHGEF11 antibody
    • DKFZp667F1223 antibody
    • Glutamate transporter EAAT4 associated protein 48 antibody
    • GTRAP 48 antibody
    • GTRAP48 antibody
    • KIAA0380 antibody
    • OTTHUMP00000038716 antibody
    • OTTHUMP00000038717 antibody
    • PDZ RHOGEF antibody
    • PDZ-RhoGEF antibody
    • Rho guanine exchange factor (GEF) 11 antibody
    • Rho guanine nucleotide exchange factor (GEF) 11 antibody
    • Rho guanine nucleotide exchange factor 11 antibody
    • RhoA specific guanine nucleotide exchange factor antibody
    • RhoGEF glutamate transport modulator antibody
    see all

Anti-ARHGEF11 antibody 图像

  • All lanes : Anti-ARHGEF11 antibody (ab110059) at 1/500 dilution

    Lane 1 : A549 cell extract
    Lane 2 : COLO cell extract
    Lane 3 : COLO cell extract with immunizing peptide

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 168 kDa

Anti-ARHGEF11 antibody (ab110059)参考文献

ab110059 has not yet been referenced specifically in any publications.

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